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Success in using Hot Melt Extrusion for treating Child Malaria


Proud to see our joint research with Queen's University Belfast and BASF has finally been published in the International Journal of Pharmaceutics!


Vertical Hot Melt Extrusion was successfully used to demonstrate the drug loading capacity of Soluplus in formulating Lumefantrine – a drug compound used as a component in the current Riamet treatment against child malaria. We found that via adjustment of extrusion conditions, dissolution performance of our F1 solutions (30 % drug loading ) even after 6 months aging , outperformed the Riamet tablets by approximately 3.5 – fold. 

A crucial step in consolidating treatment performance while reducing the current side effects… and lowering its cost!



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