Extremely proud to see our QUB RONDOL BASF hard work being recognized and published in IJP!
Vertical Hot Melt Extrusion was successfully used to demonstrate the drug loading capacity of Soluplus in formulating Lumefantrine – a drug compound used as a component in the current Riamet treatment against child malaria. We found that via adjustment of extrusion conditions, dissolution performance of our F1 solutions (30 % drug loading ) even after 6 months aging , outperformed the Riamet tablets by approximately 3.5 – fold.
A crucial step in consolidating treatment performance while reducing the current side effects… and lowering its cost!
Read the paper online here: https://www.sciencedirect.com/science/article/abs/pii/S0378517324009104