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A Comparative Overview of Hot Melt Extrusion and Spray Drying in Pharmaceutical Manufacturing

Hot Melt Extrusion and Spray Drying are two distinct technologies employed in the pharmaceutical industry to enhance drug formulations. Let’s take a closer look at these methods and compare their key features. In terms of common strong points, both Hot Melt Extrusion and Spray Drying share the goal of improving the release profile of all …

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Extrusion for pharma applications: An update

Victoire de Margerie (CEO of Rondol), Pascal Boulet (Institut Jean Lamour), and MaĂ«l Gallas (Rondol) published a new article in SPE Polymers about our current research and development on hot-melt extrusion (HME) for drug delivery and pharmaceutical formulation. Unfortunately, a large percentage of marketed drugs (40%) and those in the development pipeline (90%) are poorly water …

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Child Friendly Anti Malarials

On World Malaria Day dedicated to Innovation, RONDOL together with BASF and Queens University Belfast can display improved dissolution results of a newly formulated Fixed Dose Combination (FDC) of Artemether and Lumefantrine thanks to using hot melt #extrusion technology as a continuous manufacturing platform. FDC of Artemether (AT) and Lumefantrine (LM) are the 1st line …

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White Paper on Aspirin

1st result of the Technology cooperation between RONDOL and SEQENS announced in March. AcetylSalicylic Acid (ASA better known as Aspirin) is one of the most popular Non-Steroidal Anti-Inflammatory Drugs (NSAID) in the world. First used as pain killer, Aspirin also brings lesser-known benefits that can be essential to prevent cardiovascular events. Further applications are currently …

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Aspirin for oncology therapies

New milestone on the RONDOL SEQENS joint cooperation to improve bioavailability of selected molecules with the successful installation of our first GMP vertical extrusion line at the SEQENS LAB in Porcheville.

Rondol and Seqens Award by l’Usine Nouvelle

Happy to receive the Trophée Initiative Chimie that highlights the potential to improve bioavailability of active principles and reduce the capital intensity of their manufacturing thanks to extrusion. Follow the link below to read the entire article. https://www.usinenouvelle.com/article/relation-fournisseur-client-palmares-haut-de-gamme-pour-la-2e-edition-des-trophees-initiatives-chimie.N1778262

1st Paper in International Journal of Pharmaceutics

Great paper in International Journal of Pharmaceutics about solutions for the pharmaceutical industry in accessing continuous manufacturing technologies and allowing for efficient utilization of resources upon scale-up and mass production during global pandemics and drug shortages. This reflects a superb common common work between RONDOL, Queens University Belfast, Birmingham School of Pharma and Institut Jean …

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